OP14.01: Low serum PAPP-A values in early pregnancy and adverse pregnancy outcome

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The risk of adverse pregnancy outcome in the setting of very low first trimester maternal PAPP-A levels

Methods A retrospective analysis of 961 pregnancies with PAPP-A < 0. 3 MoM and 961 age-matched controls with PAPP-A level 0. 9-1. 1 MoM. The study period was a four years (2009-2012). The FTS was performed according to the guidelines of Finnish Ministry of Social Affairs and Health. The gestational age was estimated by the fetal crown-rump length and the NT measurement was performed according t...

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Thrombophilias and adverse pregnancy outcome.

Mousa and Alfirevic (2000) recently reported on the relationship between histological placental lesions and throm-bophilia status in women with adverse pregnancy outcomes. Their results are interesting (with apparently thorough thrombophilia testing performed), but their conclusion, that the results do not support an association between thrombophilias and adverse pregnancy outcome, is misleadin...

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Hypercholesterolaemia in pregnancy as a predictor of adverse pregnancy outcome.

BACKGROUND Prevention of viable spontaneous preterm birth and low birth weight through screening is one of the key aims of antenatal care as these have implications for the child, mother and society. If women can be identified to be at high risk of these adverse birth outcomes in early pregnancy, they can be targeted for more intensive antenatal surveillance and prophylactic interventions. OB...

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Thrombophilia and adverse pregnancy outcome.

The hemostatic system plays an important role in three crucial stages of pregnancy: ovulation, implantation, and placentation. A thrombophilic defect is an abnormality in the coagulation pathways that predisposes an individual to thrombosis. Pregnancy is a hypercoaguable state and interest has focused on the potential role that thrombophilic defects may play in the etiology not only of recurren...

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Thrombophilia and adverse pregnancy outcome.

Congenital and acquired thrombophilias are the most common predisposing factors for thromboembolism, but they may also contribute to pathophysiological processes involved in recurrent pregnancy loss, fetal death, intrauterine growth restriction, placental abruption, placental infarction, and pre-eclampsia. The most common thrombophilias are deficiencies of antithrombin III, protein C, and prote...

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ژورنال

عنوان ژورنال: Ultrasound in Obstetrics and Gynecology

سال: 2010

ISSN: 0960-7692

DOI: 10.1002/uog.8049